In keeping with the school's philosophy of educating the whole child, Villa Duchesne offers a wide range of co-curricular activities which foster the intellectual, physical, social, and spiritual development of the students. Activities and organizations are meant to build community, encourage leadership, foster social awareness, and develop within the school community a spirit of service. Clubs and other organized activities give interested students opportunities to grow and mature through additional responsibilities and commitments.

The Student Activities program also offers opportunities for academic enrichment and exploration in areas of personal interest. So that the needs and interests of today's student may be met, the faculty and administration encourage and support the development of new clubs and activities. Clubs and organizations meet during regularly scheduled activity periods and also outside of school.